| 引用本文: | 赵梓贺,万熠,于明志,张晓,王宏卫,宋章仪.激光刻蚀和阳极氧化对纯钛植入体表面性能的影响[J].中国表面工程,2020,33(6):29~36 |
| Zhao Zihe,Wan Yi,Yu Mingzhi,Zhang Xiao,Wang Hongwei,Song Zhangyi.Effects of Laser Etching and Anodic Oxidation on Surface Properties of Pure Titanium Implants[J].China Surface Engineering,2020,33(6):29~36 |
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| 激光刻蚀和阳极氧化对纯钛植入体表面性能的影响 |
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赵梓贺1,2, 万熠1,2, 于明志1,2, 张晓1,2, 王宏卫1,2, 宋章仪1,2
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1.山东大学 高效洁净机械制造教育部重点实验室, 济南 250061;2.山东大学 机械工程学院, 济南 250061
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| 摘要: |
| 钛本身为生物惰性材料,为了提高钛植入体的生物活性,制备出兼具微米级结构和纳米级结构的表面,发挥微纳米双级结构的协同效应。 采用纳秒激光刻蚀出微沟槽结构并在其表面进行阳极氧化,在钛表面制备了一种有序的微沟槽-TiO2 纳米管复合结构。 对各组不同表面结构的试件的表面形貌、粗糙度、亲水性、物相组成等进行表征。 应用生物矿化试验对不同组试件的生物活性进行评价。 与抛光表面相比,微纳米复合结构的表面粗糙度从 0. 281 μm 增加到 7. 297 μm,表面接触角从 73. 1°减小到 32. 1°,亲水性显著提高。 XRD 图谱显示,阳极氧化后经热处理的表面出现了锐钛矿(2θ= 26°)的特征峰,表明 TiO2 由无定型转变为锐钛矿型。 此外,与抛光表面和单一微/ 纳米结构表面相比,微纳组表面在模拟体液中浸泡 14 d 后沉积的羟基磷灰石层更致密。 采用激光刻蚀与阳极氧化制备的微纳复合结构可以显著提高钛表面的粗糙度和亲水性,且具有更加优异的生物活性。 此研究为在钛植入体表面构建规则的微纳米结构以改善生物活性提供了一种有效的方法。 |
| 关键词: 钛植入体 激光刻蚀 阳极氧化 微纳米结构 羟基磷灰石 生物活性 |
| DOI：10.11933/j.issn.1007-9289.20201109001 |
| 分类号:TG146;R318 |
| 文章编号:1007-9289(2020)06-0029-08 |
| 文献标识码:A |
| 基金项目:国家自然科学基金(51975336)； 山东省重点研发计划(2019JZZY010112)； 山东省自然科学基金重大基础研究项目(ZR2018ZB0106) |
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| Effects of Laser Etching and Anodic Oxidation on Surface Properties of Pure Titanium Implants |
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Zhao Zihe1,2, Wan Yi1,2, Yu Mingzhi1,2, Zhang Xiao1,2, Wang Hongwei1,2, Song Zhangyi1,2
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1.Key Laboratory of Ministry of Education for High-efficiency and Clean Mechanical Manufacture, Shandong University, Jinan 250061 , China;2.School of Mechanical Engineering, Shandong University, Jinan 250061 , China
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| Abstract: |
| Titanium and its alloys are bioinert materials. The surface with micro-scale and nano-scale structures was prepared and the synergistic effect of the micro-nano structure was used to improve the biological activity of the titanium implant. An or- dered micro-grooves and TiO2 nanotube composite structure was prepared on titanium by nanosecond laser etching and anodic oxi- dation. The surface morphology, roughness, hydrophilicity, and phase composition of Ti samples with different surface structures were characterized. Vitro mineralization experiments were used to evaluate the biological activity of samples with different groups. Results show that micro-grooves and TiO2 nanotubes are successfully constructed. Compared with polished surface, the surface roughness of the micro-nano composite structure increase from 0. 281 μm to 7. 297 μm, and the surface contact angle de- crease from 73. 1° to 32. 1°, exhibiting a better hydrophilicity. XRD patterns show that the anatase characteristic peak appeares after anodization and heat treatment, indicating that TiO2 changed from amorphous to anatase. In addition, after being immersed in the simulated body fluid for 14 days, the hydroxyapatite layer deposited on the micro-nano structured surface is thicker and denser, compared with the polished surface and the single micro / nano structured surface. All results indicated that micro-nano structure prepared by laser etching and anodic oxidation can significantly improve the roughness and hydrophilicity of the titaniumsurface, and realized more excellent biological activity. This study provides an effective method for constructing regular micro- nano structures on the surface of titanium implants to improve biological activity. |
| Key words: titanium implant laser etching anodization micro-nano structure hydroxyapatite biological activity |
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