引用本文:吴犇,陈晓艺,路怀峰,赵晓兵,王国成.等离子喷涂技术在骨植入体表面改性中的研究进展∗[J].中国表面工程,2021,34(4):1~11
WU Ben,CHEN Xiaoyi,LU Huaifeng,ZHAO Xiaobing,WANG Guocheng.Recent Progress in the Surface Modification of Bone Implant Using Plasma Spraying Technique[J].China Surface Engineering,2021,34(4):1~11
【打印本页】   【HTML】   【下载PDF全文】   【查看/发表评论】  【EndNote】   【RefMan】   【BibTex】
←前一篇|后一篇→ 过刊浏览    高级检索
本文已被：浏览 1556次   下载 782次 本文二维码信息
码上扫一扫！
分享到： 微信 更多
字体:加大+|默认|缩小-
等离子喷涂技术在骨植入体表面改性中的研究进展∗
吴犇1,2, 陈晓艺2, 路怀峰1,2, 赵晓兵1, 王国成2
1.常州大学材料科学与工程学院 常州 213164;2.中国科学院深圳先进技术研究院人体组织与器官退行性研究中心 深圳 518055
摘要:
金属植入体材料已广泛用于各种硬组织相关疾病的治疗,但金属植入体表面的骨整合和抗菌能力不足,往往导致临床植入手术失败。 表面改性能够在保持金属材料优异力学性能的同时,针对性地改善其表面特性,目前广泛用于解决金属植入体存在的骨整合能力差和缺乏抗菌性能等问题。 在众多表面改性技术中,等离子喷涂因性价比高、工艺成熟、原料可选择范围广及可大规模生产等优点,目前已在人工关节和牙种植体表面改性方面获得商业化应用。 从提高植入体成骨活性、抗感染能力及骨免疫调节能力等方面介绍等离子喷涂技术的优势及其在金属植入体表面改性方面的研究进展,阐述等离子喷涂技术在优化骨科植入体表面化学性质方面的优势,并重点讨论等离子喷涂技术在制备和调控植入体表面纳米结构方面的潜在应用价值,为植入体表面设计提供借鉴。 还结合课题组前期在等离子喷涂技术领域的相关工作,提出关于等离子喷涂技术在骨植入体表面改性方面的新思路。
关键词:  表面改性  等离子喷涂  生物活性  表面形貌
DOI：10.11933/j.issn.1007-9289.20210410001
分类号:TG1174
基金项目:国家自然科学基金(51872318)和深圳国际合作(GJHZ20180420180912286)资助项目
Recent Progress in the Surface Modification of Bone Implant Using Plasma Spraying Technique
WU Ben1,2, CHEN Xiaoyi2, LU Huaifeng1,2, ZHAO Xiaobing1, WANG Guocheng2
1.School of Materials Science and Engineering, Changzhou University, Changzhou 213164 , China;2.Research Center for Human Tissues & Organs Degeneration, Shenzhen Institutes of Advanced Technology, Chinese Academy of Science, Shenzhen 518055 , China
Abstract:
Metallic implants have been widely used in the treatment of a variety of hard tissue-related diseases. However, the currently used metallic implants lack strong osteointegration and antimicrobial ability,which often leads to the implant failure. Surface modification can not only maintain the excellent bulk properties of the metal material, but also improve their surface properties. At present, surface modification has been widely used to improve the osseointegration and endow the implant with promising antibacterial functions. Among many surface modification technologies, plasma spraying has been applied commercially in surface modification of artificial joints and dental implants due to its technical maturity, high quality controllability, applicability to a wide range of raw materials and ability of continuous production, etc. In this review, the advantages of plasma spraying technology and its recent research progress in surface modification of metallic implants were introduced from aspects of improving osteogenic activity, providing antibacterial functions and enhancing bone immunomodulation ability of the implant, and the advantages of plasma spraying technology in optimizing surface chemical properties of orthopedic implants were described. The advantages and potential application of plasma spraying technology in the fabrication and modulation of surface nanostructures of the coating were discussed, which could provide new reference for the surface design of biomedical implants. In addition, combined with our work related to plasma spray related to biomedical coatings, some perspectives about new possible application of plasma spraying technology in enhancing the performance of bone implants were proposed.
Key words:  surface modification  plasma spraying  biological activity  surface morphology
手机扫一扫看